• BMF 82- Triclosan

    BMF 82- Triclosan

    Triclosan (5-Chloro-2-(2,4-dichlorophenoxy)phenol; Cat. No. 8472.12) is an antimicrobial agent extensively used in soaps, shampoos, deodorants, toothpaste etc. and the content typically varies from 0.1-1%.

    Triclosan is a white crystalline substance with structural similarities to dibenzo-p-dioxins and dibenzofurans. Its mechanisms of action, risk of bacterial resistance and its possible role in disruption of hormonal development has been controversial.

    Our interest in triclosan increased following purification of a commercial sample by repeated crystallizations, which yielded the PCDF 2,4,8-trichlorodibenzofuran (Cat. No. 11789.12) rather than triclosan itself.

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  • BMF 76- Drinking Water Quality

    BMF 76- Drinking Water Quality

    Clean and safe drinking water is essential for life! Therefore water quality, as well as taste and odour, are highly regulated and monitored. It is also a matter of public trust in your local drinking water.Off-flavours of drinking water are often taints of either products from microorganisms or from food products.Some algae, particularly blue-green algae (cyanobacteria) such as Anabaena, produce 2-methylisoborneol (MIB) together with other odourous chemicals such as geosmin. These two compounds typically affect the flavour of drinking water or fish living in that water.Geosmin has a distinct earthy flavour and taste, while 2-methylisoborneol (MIB) gives a musty and earthy flavour to water and is often associated with algal blooms. MIB is also a factor in cork-taint in wine-making.
     
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  • BMF 74 - Simultaneous Monitoring of 2-MCPD, 3-MCPD

    BMF 74 - Simultaneous Monitoring of 2-MCPD, 3-MCPD

    Monochloropropane-1,2-diol (MCPD) and its ester are food borne contaminants, mainly formed during high temperature processing of fat-containing matrices. Maximum levels of less than 2 µg MCPD per kilogram body weight per day have been established by Commission Regulation (EC) 1881/2006. The European Food Safety Authority (EFSA) Panel on Contaminants in the Food Chain (CONTAM) agreed with the estimate of 100 % release of 3-MCPD from its esters in humans.

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  • BMF 29 - Food Safety I

    BMF 29 - Food Safety I

    Highly Purified Natural Toxins for Food Analysis

    Chiron has built up a strong track record of supplying new reference standards during the past 30 years of operation. We are proud to announce our extended offer of Highly Purified Natural Toxins for Food Analysis.

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  • BMF 30 - Food Safety II

    BMF 30 - Food Safety II

    Chiron has built up a strong track record of supplying new reference standards during the past 30 years of operation. We are proud to announce our offer of Contaminants and Impurities for Food Analysis. In this leaflet you will find analytes within the following categories.

     

    Toxic compounds formed during food processing:
    3-MCPD and Glycidyl fatty acid ester, Acrylamide, Furan, Stigmastadienes, PAH´s

     

    Food packaging contaminants:
    Plasticizers, 2-Ethylhexanoic acid, SEM, Ethyl carbamate, ITX

     

    Environmental contaminants:
    PFOS / PFC´s, Pesticides and other POPs

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  • BMF 31 - Food Safety III

    BMF 31 - Food Safety III

    Chiron has built up a strong track record of supplying new reference standards during the past 28 years of operation. We are now proud to announce our offer of Food Colour and Food Aroma reference materials.

    Food Colours: Carotenoids, Chlorophylls, Synthetic colours

    Food Aroma: Taste and Flavours

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  • BMF 32 - Plasticizers: Phthalates and Adipates

    BMF 32 - Plasticizers: Phthalates and Adipates

    Phthalate and adipate esters are widely used as surfactants and in food and personal care products as plasticizers. Phthalates and adipates are also found in food as a result of leakage into food containers. Chiron offers a wide range of analytically pure deuterated and native phthalates and adipates, as well as mixes. Custom made mixes are available on request.

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  • BMF 47 - Allergens European standard CEN/TC 347/WG 4N 19

    BMF 47 - Allergens European standard CEN/TC 347/WG 4N 19

    24 Suspected allergens in analytical purity.

    Safe and accurate analysis of priority suspected allergens has been hampered by the lack of pure and reliable standards. Many of the known allergens have only been available as mixtures of isomers or impure compounds, and purities stated by various fine chemical suppliers has proven to be unreliable for most of these substances. Chiron has purified each individual allergen in order to obtain a reliable standard mixture of the 24 suspected compounds as suggested in the new
    CEN/TC347/WG 4N 19 method, altogether 26 isomers.

     

    Chiron AS offers highly purified substances for allergen analysis and toxicological studies, as well as a convenient all-in-one mixture.

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  • BMF 48 - Melamine-15N3

    BMF 48 - Melamine-15N3

    Melamine is a trimer of cyanamide with a 1,3,5-triazine skeleton. It contains 66% nitrogen by mass and, if mixed with resins, has fire retardant properties due to release of nitrogen. It is most commonly encountered as melamine resin in combination with formaldehyde, which is a very durable thermosetting plastic used among other things for dinnerware, countertops and cooking spoons.

     

    Melamine has been added to low quality pet food and infant formula to make the protein content appear higher than it actually is. Simple protein tests uses nitrogen content as a measure for proteins, and addition of protein-rich compounds like melamine therefore alters the results.

     

    Chiron AS offers both native and 15N-labelled melamine for analytical work, as well as the related metabolites like ammeline and ammedine.

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  • BMF 49 - 3-Monochloropropanediol esters (3-MCPD esters)

    BMF 49 - 3-Monochloropropanediol esters (3-MCPD esters)

    Over the last years, there has been an increase in interest for 3-MCPD fatty acid esters in food analysis. These esters are formed during production and heating of oils and fats, and are considered harmful at a high level of consumption.

     

    3-MCPD is a known carcinogen found as a heat-induced contaminant in many different types of fat-containing foodstuffs. The European Food Safety Authority (EFSA) has defined a limit of 2μg/kg body weight as a tolerable daily intake (TDI).

     

    Chiron AS offers highly purified 1-mono- and diesters, both native and deuterated, for analytical work and for toxicological studies, as well as free 3-MCPD.

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  • BMF 50 - Mixed phthalates

    BMF 50 - Mixed phthalates

    Certain phthalates are listed on the CANDIDATE LIST OF SUBSTANCES OF VERY HIGH CONCERNFOR AUTHORIZATION by ECHA, the European Chemicals Agency:

     

    Dibutyl phthalate
    Diisobutyl phthalate
    Benzyl butyl phthalate
    Bis(2-ethylhexyl) phthalate
    Bis(2-methoxyethyl)phthalate

     

    UNIQUE in-house proprietary technology enables Chiron to offer pure mixed phthalate-esters in sufficient quantities for toxicological and analytical purposes. In contrary to traditional synthesis methods were transesterification is a problem, the new method enables us to synthesize these esters is pure separated isomeric forms.

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  • BMF 55 - Nitrosamines and Nitramines

    BMF 55 - Nitrosamines and Nitramines

    It is well known that nitrosamines and nitramines can be dangerous to human health, animals and plant lives. There are several technologies which release them into the environment.

     

    Nitrosamines are a class of chemical compounds that have received much attention since 1956, when two British scientists, John Barnes and Peter Magee, reported that dimethylnitrosamine produced liver tumors in rats. Nitrosamines are formed by reactions of nitrites and secondary amines (e.g. in proteins) under acidic conditions like gastric milieus. Human beings ingest nitrites from food, esp. fried or grilled meat and vegetables. Disposal of tobacco products also causes a high intake of nitrosamines (mainly N-Nitrosonornicotin).

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  • BMF 56 - Glycidyl fatty acid esters

    BMF 56 - Glycidyl fatty acid esters

    Over the last years, there has been an increase ininterest for 3-MCPD fatty acid esters and glycidyl fatty acid esters in food analysis. These esters are formed during production and heating of oils and fats, and are thought to be harmful at a high level of consumption.

     

    Chiron AS now offers highly purified glycidyl fatty acid esters for use as reference standards in food analysis, as well as an internal standard and free glycidol.

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  • BMF 57 - PAH metabolites

    BMF 57 - PAH metabolites

    The major source of PAHs is incomplete combustion of organic material like coal, oil or wood. Except of breathing in contaminated air from e.g. cigarette smoke or a fire place, eating food is a significant source of PAHs for humans, too. Exposure to PAHs means always a mixture of PAHs - therefore the dynamics of metabolism are important and dependent on composition of the mixture.

     

    Chiron AS offers a broad selection of PAH Nitro-/Amino- and Hydroxy-/Keto Metabolites as reference materials

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  • BMF 64 - Parabens

    BMF 64 - Parabens

    Parabens are a class of chemicals widely used as preservatives in personal care, cosmetic, pharmaceutical and food products since the 1930s. Parabens are esters of para-hydroxybenzoic acid (Fig.1) with methylparaben, ethylparaben, propylparaben, and butylparaben being most commonly used. Parabens and their salts are used for antimicrobial properties. They are detected in waste water, rivers, soil and house dust, hence human exposure is ubiquitous throughout life. Due to their omnipresent nature parabens are usually detected in human tissues and fluid samples although they are excreted relatively quickly. Although parabens are still widely considered to be safe, health concerns have been raised since studies have shown that parabens are found in breast tissue from patients with breast cancer.

     

    Chiron is happy to offer a variety of parabens including internal standards. Native reference materials are available as neat material, or as a solution in methanol. Internal standards are available as a solution in methanol. 

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  • BMF 73 - Sunscreen agents

    BMF 73 - Sunscreen agents

    Sunscreen protects us from UV radiation and can be effective in preventing acute sunburns, skin cancer and skin aging. However several studies suggest that some sunscreen ingredients like padimate O, octinoxate, homosalate and oxybenzone show estrogenic activity. This effect was mainly observed if combinations of them were used in sunscreen. It is becoming necessary to look more deeply into this potential health risks to guarantee the long-term safety of sunscreen.

     

    Chiron is happy to offer a variety of sunscreen ingredients including internal standards. Native reference materials are available as neat material. Internal standards are available as a solution in methanol. 

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  • BMF 59 - Cyclic Siloxanes

    BMF 59 - Cyclic Siloxanes

    Cyclic siloxanes are used in the manufacturing of silicones, in combination or alone in personal care products, and as carriers, lubricants and solvents in a variety of commercial applications. They are of interest due to their extensive use and the fact that certain siloxanes are persistent in the environment, resisting oxidation, reduction, and photodegradation.

    Recently, the use of cyclosiloxanes in cosmetics and personal care products has received increased attention. Organizations like Environment Canada, Office of Environmental Health Hazard Assessment (OEHHA), and Norwegian Institute for Air Research (NILU) have released reports on the distribution of cyclosiloxanes in the environment and their potential health and environmental effects. 

     

    Chiron AS now offers high quality standards for analysis of cyclic siloxanes surfactants– get 15% discount when purchasing the whole set!

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Chiron AS, Stiklestadveien 1, NO-7041 Trondheim, Norway T: +47 73 87 44 90 F: +47 73 87 44 99 E: sales@chiron.no Contact us